NSCCN/haploclique：用于病毒群体中的单倍型组装和变异解析。

cbg-ethz/haploclique

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Armin Töpfer

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We present a novel method to reconstruct the structure of a viral quasispecies from NGS data. Our approach can be used to:

reconstruct local error-corrected haplotypes and estimate their abundance
assemble full-length viral haplotypes
detect large deletions and insertions from paired-end data.

Reference implementation of:

Armin Töpfer, Tobias Marschall, Rowena A. Bull, Fabio Luciani, Alexander Schönhuth, and Niko Beerenwinkel. Viral quasispecies assembly via maximal clique finding PLOS Computational Biology, 2014.

Documentation

Contributions

Armin Töpfer
Tobias Marschall
Maryam Zaheri
Bernhard Lang
Marcel Meyerheim
The HaploClique implementation was derived from CLEVER

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用于病毒群体中的单倍型组装和变异解析。

病毒单倍型群体测序变异重建生物医药健康 c++cmake

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